The Dielectrophoresis Network

at the University of Surrey

Graphic1

Electromics

An electrome is the totality of the electrical properties of a cell.  

 

For a simple cell, this includes the membrane potential Vm, surface electrokinetic (zeta) potential properties from DEP such as cytoplasm conductivity and membrane conductance and capacitance; and low-freuqency polarisation effects.  A more complicated cell would include mitochondrial membrane potentials, possible nuclear membrane potentials, and the effects of gap junctions to neighbouring cells.

 

We have been working to develop a theory that encompasses the cellular electrome, starting with the simples functional electrical cell, the red blood cell (RBC).  We are also developing models for platelets.  The models suggest explanations of observed cellular behaviour in developmental and cancer biology, and may have a significant impact on the way we understand how cells interact.

 

The work is currently in preparation for publication, and we will have more details once that has been achieved.

Final Fig 1a